Hot Search
Preservation Solution Extraction Machine DNA Extraction Kit Blood card puncher 28A 23sp Y Prime Plus RM-Y 19X Fragile X SMN AZF Deafness Folic Acid MSI CE Cardiovascular Drugs CYP2C19, CYP2C9, VKORC1

Clinical Research

Cardiovascular Drugs
Index  > - Clinical Research  > - Cardiovascular Drugs

Cardiovascular Drugs

Multi-fluorescent PCR-capillary electrophoresis was used to detect gene polymorphisms, which could help to identify cardiovascular drug sensitivity of patients in clinic.


Features

■ Comprehensive:
Genotype the genes related to all the cardiovascular drugs mentioned above at one time.
■ Convenience：
Direct PCR amplification from blood card or EDTA-anticoagulated whole blood in a single tube, applicable for automatic and batched detection.
■ Fast:

Get result within 3 hours, with manual operation time less than 20 minutes.


Workflow

Instrument

Gene analyzer (ABI PRISM 310, 3100 Genetic Analyzer, or ABI 3130 Series, 3500 Series, 3730 Series Genetic Analyzer)

Sample types

Peripheral blood, blood stain

Applied population

Hypertension, hyperlipidemia, atherosclerosis, coronary heart disease and other cardiovascular and cerebrovascular diseases patients.

Clinical significance

The genetic variation of drug metabolism, transport, target genes and their expression level can affect drug concentration and sensitivity, leading to individual differences in drug reactivity. 

Detection of drug metabolic enzymes and drug target genes can guide clinicians to make drug and dosage choices for specific patients, to achieve individualized drug usage, so as to improve the effectiveness and safety of drug treatment and prevent the occurrence of serious adverse drug reactions.